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Shiau C, Cao J, Gong D, Gregory MT, Caldwell NJ, Yin X, Cho JW, Wang PL, Su J, Wang S, Reeves JW, Kim TK, Kim Y, Guo JA, Lester NA, Bae JW, Zhao R, Schurman N, Barth JL, Ganci ML, Weissleder R, Jacks T, Qadan M, Hong TS, Wo JY, Roberts H, Beechem JM, Castillo CF, Mino-Kenudson M, Ting DT, Hemberg M, Hwang WL
Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment.
Nat Genet. 2024;56(11):2466-2478 - PMID: 39227743 - PMCID: PMC11816915 - DOI: 10.1038/s41588-024-01890-9
Kang M, Quintana J, Hu H, Teixeira VC, Olberg S, Banla LI, Rodriguez V, Hwang WL, Schuemann J, Parangi S, Weissleder R, Miller MA
Sustained and Localized Drug Depot Release using Radiation-Activated Scintillating Nanoparticles.
Adv Mater. 2024;36(23):e2312326 - PMID: 38389502 - PMCID: PMC11161319 - DOI: 10.1002/adma.202312326
Halabi EA, Gessner I, Yang K, Kim JJ, Jana R, Peterson HM, Spitzberg J, Weissleder R
Magnetic Silica-Coated Fluorescent Microspheres (MagSiGlow) for Simultaneous Detection of Tumor-Associated Proteins.
Angew Chem Int Ed Engl. 2024;63(24):e202318870 - PMID: 38578432 - PMCID: PMC11998990 - DOI: 10.1002/anie.202318870
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
J Extracell Vesicles. 2024;2:e12404 - PMID: 38326288 - PMCID: PMC10850029 - DOI: 10.1002/jev2.12404
Kartal B, Garris CS, Kim HS, Kohler RH, Carrothers J, Halabi EA, Iwamoto Y, Goubet AG, Xie Y, Wirapati P, Pittet MJ, Weissleder R
Targeted SPP1 Inhibition of Tumor-Associated Myeloid Cells Effectively Decreases Tumor Sizes.
Adv Sci (Weinh). 2024;12(4):e2410360 - PMID: 39639496 - PMCID: PMC11775521 - DOI: 10.1002/advs.202410360
Enbergs N*, Halabi EA*, Goubet AG, Schleyer K, Fredrich IR, Kohler RH, Garris CS, Pittet MJ, Weissleder R
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype.
Adv Sci (Weinh). 2024;11(15):e2309026 - PMID: 38342608 - PMCID: PMC11022742 - DOI: 10.1002/advs.202309026
Quintana JM, Kang M, Hu H, Ng TSC, Wojtkiewicz GR, Scott E, Parangi S, Schuemann J, Weissleder R, Miller MA
Extended Pharmacokinetics Improve Site-Specific Prodrug Activation Using Radiation.
ACS Cent Sci. 2024;10(7):1371-1382 - PMID: 39071065 - PMCID: PMC11273447 - DOI: 10.1021/acscentsci.4c00354
Das R, Ge X, Fei F, Parvanian S, Weissleder R*, Garris CS*
Lipid Nanoparticle-mRNA Engineered Dendritic Cell Based Adoptive Cell Therapy Enhances Cancer Immune Response.
Small Methods. 2024;9(1):e2400633 - PMID: 39039995 - PMCID: PMC11740962 - DOI: 10.1002/smtd.202400633
Kim HS, Halabi EA, Enbergs N, Kohler RH, Fei F, Garris CS, Weissleder R
A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation.
Theranostics. 2024;14(7):2934-2945 - PMID: 38773971 - PMCID: PMC11103498 - DOI: 10.7150/thno.95267
Gopal AA, Fernandez B, Delano J, Weissleder R, Dubach JM
PARP trapping is governed by the PARP inhibitor dissociation rate constant.
Cell Chem Biol. 2024;31(7):1373-1382.e10 - PMID: 38262416 - PMCID: PMC11259578 - DOI: 10.1016/j.chembiol.2023.12.019
Sarkar B, Arlauckas SP, Cuccarese MF, Garris CS, Weissleder R, Rodell CB
Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype
Frontiers in Immunology (molecular innate immunity section). 2024;15:1331480 - PMID: 38545103 - PMCID: PMC10965546 - DOI: 10.3389/fimmu.2024.1331480
van Solinge TS, Oh J, Abels E, Koch P, Breakefield XO, Weissleder R, Broekman MLD
Probing the glioma micro-environment: analysis using biopsy in combination with ultra-fast cyclic immunolabeling.
Neoplasia. 2024;57:101051 - PMID: 39270598 - PMCID: PMC11415813 - DOI: 10.1016/j.neo.2024.101051
Deutsch-Williams RJ, Schleyer KA, Das R, Carrothers JE, Kohler RH, Vinegoni C, Weissleder R
FAP-Targeted Fluorescent Imaging Agents to Study Cancer-Associated Fibroblasts In Vivo.
Bioconjug Chem. 2024;36(1):44-53 - PMID: 39667730 - PMCID: PMC11740949 - DOI: 10.1021/acs.bioconjchem.4c00426
Landeros C, Oh J, Weissleder R, Lee H
Deep learning pipeline for automated cell profiling from cyclic imaging
Sci Rep. 2024;14(1):23600 - PMID: 39384907 - PMCID: PMC11464789 - DOI: 10.1038/s41598-024-74597-w
Quintana JM, Carlson JCT, Scott E, Ng TSC, Miller MA, Weissleder R
Scission-Enhanced Molecular Imaging (SEMI).
Bioconjug Chem. 2024;35(10):1543-52 - PMID: 39255972 - PMCID: PMC11488501 - DOI: 10.1021/acs.bioconjchem.4c00337
Schleyer K, Halabi EA, Weissleder R
γ-Butyrolactone derivatives of MSA-2 are STING prodrugs
ChemMedChem. 2024;19(19):e202400416 - PMID: 38887174 - PMCID: PMC11979874 - DOI: 10.1002/cmdc.202400416
Uygun K, von Reiterdank IF, Mojoudi M, Bento R, Taggart M, Dinicu A, Wojtkiewicz G, Coert J, van der Molen AM, Weissleder R, Parekkadan B
Ex Vivo Machine Perfusion as a Platform for Lentiviral Gene Delivery in Rat Livers.
Res Sq. 2024;:ePub - PMID: 39315250 - PMCID: PMC11419271 - DOI: 10.21203/rs.3.rs-4784505/v1
Quintana JM, Jiang F, Kang M, Valladolid Onecha V, Könik A, Qin L, Rodriguez VE, Hu H, Borges N, Khurana I, Banla LI, Le Fur M, Caravan P, Schuemann J, Bertolet A, Weissleder R, Miller MA, Ng TSC
Localized in vivo prodrug activation using radionuclides.
bioRxiv. 2024;:ePub - PMID: 39211146 - PMCID: PMC11361159 - DOI: 10.1101/2024.08.02.606075
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